NOUVEAU COMPOSE DE PYRIMIDINE, SON PROCEDE DE PREPARATION ET COMPOSITION PHARMACEUTIQUE LE CONTENANT EN TANT QUE PRINCIPE ACTIF POUR LA PREVENTION OU LE TRAITEMENT DU CANCER ET DES MALADIES INFLAMMATOIRES
LEE, KWANGHO,CHOI, GILDON,LEE, NA RI,PARK, SANG JUN,JUNG, MYOUNG EUN,KIM, SEONG JIN,YANG, KYUNG-MIN,LEE, JIHEE
申请号:
CA3043295
公开号:
CA3043295A1
申请日:
2017.11.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to a novel pyrimidine compound, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer and inflammatory diseases. The novel pyrimidine compound according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-ß, which is known to suppress cancer growth, and thus the novel pyrimidine compound can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory diseases.