NOUVEAU COMPOSÉ DE PYRIMIDINE, SON PROCÉDÉ DE PRÉPARATION ET COMPOSITION PHARMACEUTIQUE LE CONTENANT EN TANT QUE PRINCIPE ACTIF POUR LA PRÉVENTION OU LE TRAITEMENT DU CANCER ET DES MALADIES INFLAMMATOIRES
LEE, Kwangho,CHOI, Gildon,LEE, Na Ri,PARK, Sang Jun,JUNG, Myoung Eun,KIM, Seong Jin,YANG, Kyung-Min,LEE, Jihee
申请号：
EP17868973
公开号：
EP3539951A4
申请日:
2017.11.01
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates to novel pyrimidine compounds, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating cancer and inflammatory disease. The novel pyrimidine compounds according to the present invention remarkably inhibits activity of DRAK that inhibits signal systems of TGF-β, which is known to suppress cancer growth, and thus the novel pyrimidine compounds can be used as a pharmaceutical composition for preventing or treating cancer and can be used as a pharmaceutical composition for preventing or treating inflammatory disease.
