A method for controlling undesired vegetation at a plant cultivation site is provided which comprises the steps of providing at said site a plant comprising at least a nucleotide sequence encoding a wild type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut HPPD) which is resistant or tolerant to a coumarone derivative herbicide and /or a nucleotide sequence encoding a wild type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut HST) which is resistant or tolerant to a coumarone derivative herbicide and applying to said site an effective amount of said herbicide. Plants comprising mut HPPD and methods of obtaining such plants are also provided.