A method for controlling undesired vegetation at a plant cultivation site is provided, which comprises the steps of providing, at said site, a plant comprising at least a nucleotide sequence encoding a wild-type hydroxyphenyl pyruvate dioxygenase or a mutated hydroxyphenyl pyruvate dioxygenase (mut-HPPD) which is resistant or tolerant to a coumarone-derivative herbicide and/or a nucleotide sequence encoding a wild-type homogentisate solanesyl transferase or a mutated homogentisate solanesyl transferase (mut-HST) which is resistant or tolerant to a coumarone-derivative herbicide applying to said site an effective amount of said herbicide. Plants comprising mut-HPPD and methods of obtaining such plants are also provided.