The present invention relates a pharmaceutical composition comprising pyrrolo six-member heterocyclic compound or its medicinal salt thereof. In particular, the present invention relates a pharmaceutical composition comprising 5-(2-Diethylamino-ethyl)-2-(5-fluoro-2-oxo-1,2-dihydro-indol-3-lylidenemethyl-methyl)-3-methyl-1,5,6,7-tetr ahydro-pyrrolo[3,2-c]pyridin-4-one or its pharmacologically acceptable salt and at least one water-soluble filler. The composition has the characteristics of rapid dissolution and good stability.本發明提供了一種含有吡咯并六員雜環化合物或其可藥用鹽的藥物組成物。具體而言,本發明提供了一種藥物組成物,含有5-(2-二乙胺基-乙基)-2-(5-氟-2-酮基-1,2-二氫-吲哚-3-亞基-甲基)-3-甲基-1,5,6,7-四氫-吡咯[3,2-c]吡啶-4-酮或其藥理學上可接受的鹽,以及至少一種水溶性填充劑。本發明的藥物組成物具有溶出迅速、穩定性良好的特點。