The invention relates to a tamper-resistant tablet comprising a matrix material in an amount of more than one third of the total weight of the tablet and a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide and form a discontinuous phase within the matrix material which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.