The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet and (ii) a plurality of coated particulates in an amount of less than two thirds of the total weight of the tablet wherein said particulates comprise a pharmacologically active compound and a physiologically acceptable polymer, preferably a polyalkylene oxide and form a discontinuous phase within the matrix material which preferably provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur. and method of using said tablet to treat pain and other conditions.
