PREPARATION OF EXTREMELY SMALL AND UNIFORM SIZED, IRON OXIDE-BASED PARAMAGNETIC OR PSEUDO-PARAMAGNETIC NANOPARTICLES AND MRI T1 CONTRAST AGENTS USING THE SAME
HYEON, TAEG HWAN,KIM, BYUNG HYO,LEE, NO HYUN,KIM, EUNG GYU,JEON, BONG SIK,KWON, EUN BYUL,PARK, JU YOUNG,MYEONG, WAN JAE
申请号:
EP11814840
公开号:
EP2600903A4
申请日:
2011.08.05
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided are a preparation method of iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles, iron oxide-based nanoparticles prepared by the same, and a T1 contrast agent including the same. More particularly, the disclosure describes a method for preparation of iron oxide nanoparticles having a extremely small and uniform size of 4 nm or less based on thermal decomposition of iron oleate complex, iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles prepared by the same, and a T1 contrast agent including iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles.