Preparation of extremely small and uniform sized, iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles and MRI T1 contrast agents using the same
Hyeon, Taeg Hwan,Kim, Byung Hyo,Lee, No Hyun,Kim, Eung Gyu,Jeon, Bong Sik,Kwon, Eun Byul,Park, Ju Young,Myeong, Wan Jae
申请号:
AU2011286527
公开号:
AU2011286527B2
申请日:
2011.08.05
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Provided are a preparation method of iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles, iron oxide-based nanoparticles prepared by the same, and a T1 contrast agent including the same. More particularly, the disclosure describes a method for preparation of iron oxide nanoparticles having a extremely small and uniform size of 4nm or less based on thermal decomposition of iron oleate complex, iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles prepared by the same, and a Tl contrast agent including iron oxide-based paramagnetic or pseudo-paramagnetic nanoparticles.