A topical composition for treatment of conditions marked by elevated skin pH may include a partially neutralized carbomer vehicle neutralized to a pH less than or equal to 5. The topical composition may be formulated to undergo continued neutralization in situ to lower skin pH toward healthy levels. The topical composition may be water-based, substantially alcohol free or both. The topical composition may include active medication such as one or more antifungal actives, natural antimicrobial agents such as oils, or a combination thereof.
