WANG, XIAODONG,ZHANG, DEHUI,FRYE, STEPHEN,KIREEV, DMITRI
申请号:
CA2945128
公开号:
CA2945128A1
申请日:
2015.04.03
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention includes pyrimidine compounds that selectively inhibit Mer tyrosine kinase (MerTK) activity and/or Tyro3 tyrosine kinase activity, and use of these pyrimidine compounds as anti-cancer agents, immunostimulatory and immunomodulatory agents, anti-platelet agents, anti-infective agents, and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.