MERTK-SPECIFIC PYRAZOLOPYRIMIDINE COMPOUNDS

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专利权人:

The University of North Carolina at Chapel Hill

发明人:

Xiaodong Wang,Stephen Frye

申请号：

US14678678

公开号：

US20150291605A1

申请日:

2015.04.03

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention includes pyrazolopyrimidine compounds of Formula I that selectively inhibit Mer tyrosine kinase (MerTK) activity and/or Tyro3 tyrosine kinase activity, and use of these pyrazolopyrimidine compounds as anti-cancer agents, immunostimulatory and immunomodulatory agents, anti-platelet agents, anti-infective agents, and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/