Glicinicos Derivatives of azabiciclo [2.2.2] octane, Pharmaceutical compositions containing them and Use thereof for treating inflammatory diseases or Respiratory broncoobstructivas
Claim 1: a compound (1) having the properties of a common equation, wherein R1 is selected from a group consisting of - H, C1-10 linear or separable tar, alquenilo c2-6, arilo, C3-8, c5-10, C1-6 and heteromorphism, Optionally replaced by one or more alternatives selected from the halogen group.-SH -NO2 -N (R5) (R6)-CN -CON (R5) 2 -NHCO (R5)-COR5, -CO2R5, C1-10 alkylsulfanyl, C1-10 alkylsulfinyl, C1-10 alkylsulfonyl, C1-10 alkyl, C1-10 alkylcarboxyl, C1-10 alkoxy, aryl, aryloxy and heteroaryl； G is selected from the group consisting of -OC (O) -,-SO2- y -C (O) -R2 is selected from a group consisting of - H, C1-10 and arilalquilo C1-6, optionally replaced by one or more alternatives selected from the halogen group.-SH -NO2 -N (R5) 2 -CN -CON (R5) 2 -NHCO (R5)-CO (R5)-CO2 (R5)C 1-10 alkylsulfanyl, C 1-10 alkylsulfinyl, C 1-10 alkylsulfonyl, C 1-10 alkyl, C 1-10 alkylcarboxyl, C 1-10 alkoxy, aryl, aryloxy and heteroaryl； R3 is selected from the group consisting of -H, C1-10 alkyl, aryl, C3-8 cycloalkyl, heteroaryl, C1-6 arylalkyl and C1-6 heteroarylalkyl, optionally substituted with one or more substituents selected from the group consisting of halogen atoms, -OH, oxo (= O),-SH -NO2 -N (R5) 2 -CN -CON (R5) 2 -NHCO (R5)-CO (R5)-CO2 (R5)C 1-10 alkylsulfanyl, C 1-10 alkylsulfinyl, C 1-10 alkylsulfonyl, C 1-10 alkyl, C 1-10 alkylcarboxy, C 1-10 alkoxy, aryl, aryloxy, C 1-10 arylalkyleneoxy and heteroaryl； R6 is selected from the group consisting of the residues of the formula group (i),(II) (III) and (IV),Where M = 1, 2 or 3； n = 1, 2 or 3； a = physiologically acceptable anion； R4 is a set of formulas: - (CH2) P -- (CH2) P - (CH2) q-w, where p is an integer between 0 or 1 to 4； q is an integer between 0 or 1 to 4； P is not or from - O -,- yes.-So...-SO2...-C (O) --N (R5) --CH=CH---N (R5) (SO2) --N (R5) (COO) --N (R5) (C (O)) --S (O2) N (R5) --CO (O) N (R5) - y -C (O) N (R5) -W is selected from a group consisting of H, C1-10 linear or separator, alquenilo c2-6, arilo, cycloq
