JANET L GUNZNERTOSTE,JOHN A FLYGARE,LUKE MASTERSON,THOMAS PILLOW
申请号：
BR112014009050
公开号：
BR112014009050A2
申请日:
2012.10.12
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
A conjugate of formula (A): where Y is selected from a single bond, and a group of formulae A1 or A2: where N shows where the group binds to the N10 of the PBD moiety； RL1 and RL2 are independently selected from H and methyl, or together with the carbon atom to which they are bound form a cyclopropylene group； CBA represents a cell binding agent； Q is independently selected from O, S and NH； R11 is either H, or R or, where Q is O, SO3M, where M is a metal cation.
