John A. Flygare,Janet L. Gunzner-Toste,Thomas Pillow,Philip Wilson Howard,Luke Masterson
申请号：
US13650277
公开号：
US20130266595A1
申请日:
2012.10.12
申请国别(地区):
US
年份:
2013
代理人:
摘要：
A conjugate of formula (A):where Y is selected from a single bond, and a group of formulae A1 or A2:where N shows where the group binds to the N10 of the PBD moiety；RL1 and RL2 are independently selected from H and methyl, or together with the carbon atom to which they are bound form a cyclopropylene group；CBA represents a cell binding agent；Q is independently selected from O, S and NH；R11 is either H, or R or, where Q is O, SO3M, where M is a metal cation.
