CAI, ANN,NGO, CAM,RAJU, T. SHANTHA,SCALLON, BERNARD
申请号：
DK06774442
公开号：
DK1896071T3
申请日:
2006.06.30
申请国别(地区):
DK
年份:
2015
代理人:
摘要：
The properties of an Fc-containing protein, for example, an antibody, are controlled by altering the sialylation of the oligosaccharides in the Fc region. The modified Fc-containing proteins have therapeutic utility in diseases or conditions in which it is desirable to control the affinity for one or more of the FcgRI, FcgRIIA, and FcgRIIIA receptors, ADCC activity, macrophage or monocyte activation, serum half-life, and avidity.
