A method of treating skin in a subject is provided. A method of reducing an appearance or effect of aging in a subject is also provided. Methods of improving skin integrity and/or skin surface topology in a subject are further provided. The methods comprise administering an effective amount of a preparation comprising ammonia oxidizing microorganisms to the subject. Related preparations and kits are also provided.本發明提供治療個體皮膚之方法。本發明亦提供減輕個體老化之外觀或影響之方法。本發明另外提供改善個體皮膚完整性及/或皮膚表面形態之方法。該等方法包括向該個體投與有效量之包括氨氧化微生物之製劑。本發明亦提供相關製劑及套組。
