ANTI-FOLR1 IMMUNOCONJUGATES AND ANTI-PD-1 ANTIBODY COMBINATIONS

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专利权人:

ImmunoGen, Inc.;Merck Sharp & Dohme Corp.

发明人:

Rodrigo R. RUIZ SOTO

申请号：

US15979989

公开号：

US20180333503A1

申请日:

2018.05.15

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-PD-1 antibodies or antigen-binding fragments thereof (e.g., pembrolizumab) are provided. Methods of administering the combinations to treat cancers, e.g., ovarian, peritoneal, or fallopian tube cancers, with greater clinical efficacy and/or decreased toxicity are also provided.

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中国工程科技知识中心

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