IMMUNOCONJUGUES ANTI-FOLR1 ET COMBINAISONS D'ANTICORPS ANTI-PD-1

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专利权人:

MERCK SHARP & DOHME CORP.;IMMUNOGEN, INC.

发明人:

RUIZ SOTO, RODRIGO R.

申请号：

CA3063893

公开号：

CA3063893A1

申请日:

2018.05.15

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-PD-1 antibodies or antigen-binding fragments thereof (e.g., pembrolizumab) are provided. Methods of administering the combinations to treat cancers, e.g., ovarian, peritoneal, or fallopian tube cancers, with greater clinical efficacy and/or decreased toxicity are also provided.

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中国工程科技知识中心

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