Wade BLAIR,Karin JOOSS,Amy Rachel RAPPAPORT,Ciaran Daniel SCALLAN,Leonid GITLIN
申请号:
US16612352
公开号:
US20200197500A1
申请日:
2018.05.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are alphavirus vectors that include neoantigen-encoding nucleic acid sequences derived from a tumor of a subject. Also disclosed are nucleotides, cells, and methods associated with the vectors including their use as vaccines.