Mitchell A. deLong,Jill M. Sturdivant,Cynthia L. Lichorowic,Andriy Kornilov
申请号:
US15941993
公开号:
US20180327381A1
申请日:
2018.03.30
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are arylcyclopropyl amino-isoquinoline amide compounds. In particular, the disclosure provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the disclosure are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, diseases characterized by abnormal growth, such as cancers, and inflammatory diseases. The disclosure further provides compositions containing isoquinoline amide compounds.