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BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME
专利权人:
LTD.;KAKEN PHARMACEUTICAL CO.
发明人:
Atsushi WATANABE,Yuuki SATO,Keiji OGURA,Yoshiyuki TATSUMI
申请号:
US15759125
公开号:
US20190055199A1
申请日:
2016.09.14
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided is a compound showing excellent Antifungal activity against Trichophyton fungus, which is a major causative microorganism of superficial mycosis, and high effectiveness on diseases caused by Trichophyton fungi. A biaryl derivative represented by the formula (I) or a salt thereof:wherein ring A is an optionally substituted phenyl, or an optionally substituted 5- or 6-membered ring heteroaryl (ring A may be further condensed to form an optionally substituted fused ring); Q is CH2, C═O, NH, O, S or the like; X1, X2 and X3 are CR1 or N; Y is CH or N; Z is CR2b or N; R2a and R2b are each a hydrogen atom, a halogen atom, an optionally substituted C1-C6 alkyl group, a C1-C6 haloalkyl group or the like; R2a and R2b may form, together with carbon atoms bonded thereto, an optionally substituted carbocycle, or an optionally substituted heterocycle.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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