The present invention relates to a compoundrepresented by the following formula (I):(see formula I)(wherein, W represents W A-A1-W B- (in which, W A issubstituted or unsubstituted aryl, etc., A1 is -NR1-,single bond, -C(O)-, etc., and W B is substituted orunsubstituted arylene, etc.), R is single bond, -NH-,--OCH2-, alkenylene, etc., X is -C(O)-, -CH2-, etc., and Mis, for example, the following formula:(see formula iii)(in which, R11, R12 and R13 each independently representshydrogen, hydroxyl, amino, halogen, etc., R14 is hydrogenor lower alkyl, Y represents -CH2-O-, etc., Z issubstituted or unsubstituted arylene, etc., A2 is singlebond, etc, and R10 is hydroxyl or lower alkoxy)), or saltthereof； and a medicament containing the same.This compound or salt thereof selectively inhibitsbinding of cell adhesion molecules to VAL-4 and exhibitshigh bioavailability so that it is useful as a preventiveand/or remedy for inflammatory diseases, autoimmunediseases, metastasis, bronchial asthma, rhinostenosis,diabetes, and the like.
