EMPRESA BRASILEIRA DE PESQUISA AGROPECUÁRIA EMBRAPA
发明人:
DE MELLO BRANDÃO, HUMBERTO
申请号：
EP11835368
公开号：
EP2633862A4
申请日:
2011.10.27
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
The present invention relates to a process for obtaining compositions constituted by propolis nanoparticles and to the use thereof, said nanoparticles being optionally associated to one or more substances of interest such as active ingredients, as well as, optionally, substances of secondary effect such as synergists and adjuvants. The process for obtaining the nanoparticles comprises the steps of preparing a fraction A, which consists of propolis extract dissolved in an organic solvent, to which one or m ore stabilizers and/or emulsifiers may be added, as well as, optionally, one or more substances of interest and/or of secondary effect； ii) preparing a fraction B, aqueous phase, constituted by: (ii.1) water； or (ii.2) an aqueous solution or dispersion, to which one or more stabilizers and/or emulsifiers may be added； (iii) drooping the fraction A onto the fraction B or the fraction B onto the fraction A； iv) homogenizing the mixture by mechanical stirring and spontaneous formation of nanoaprticles with average size ranging from 1 to 1000 nm in a dispersion； v) optionally the following additional steps may be involved: (v-1) removing the organic solvent/ and/or (v-2) drying the nanodispersion. The developed compositions have applications in fields such as agrochemical, pharmaceutical, cosmetic or chemical fields.
