REŽIM ODMERJANJA ZA SELEKTIVNI AGONIST RECEPTORJA SIP1

• 收藏
• 分享

专利权人:

Actelion Pharmaceuticals Ltd.

发明人:

BROSSARD Patrick,DINGEMANSE Jasper,NAYLER Oliver,SCHERZ Michael,STEINER Beat

申请号：

SI200931616

公开号：

SI2278960T1

申请日:

2009.03.12

申请国别(地区):

SI

年份:

2017

代理人:

摘要：

The present invention relates to a dosing regimen for a selective S1P1 receptor agonist, whereby the selective S1P1 receptor agonist is administered to a subject in such a way that during the initial treatment phase the selective S1P1 receptor agonist is administered at a dose which induces desensitization of the heart wherein said dose is below the target dose, and at a dosing frequency that sustains desensitization of the heart, until no further acute heart rate reduction occurs, followed by dose up-titration to the target dose of the selective S1P1 receptor agonist.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/