Roland J. BILLEDEAU,James J. CRAWFORD,Saul JAIME-FIGUEROA,Wendy LEE,Francisco Javier LOPEZ-TAPIA,Sung-Sau SO
申请号:
US16789081
公开号:
US20200181154A1
申请日:
2020.02.12
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Pyrazole carboxamide compounds of Formula I are provided, with various substituents, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.