Roland J BILLEDEAU,James J. CRAWFORD,Saul JAIME-FIGUEROA,Wendy LEE,Francisco Javier LOPEZ-TAPIA,Sung-Sau SO
申请号:
US15690140
公开号:
US20180057500A1
申请日:
2017.08.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Pyrazole carboxamide compounds of Formula I are provided, with various substituents, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.