CANNING, PETER CONNOR,KNUDSEN, NICKOLAS,SKIDMORE, LILLIAN
申请号：
CA3028683
公开号：
CA3028683A1
申请日:
2017.06.16
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Disclosed herein are porcine interferon alpha variants (pINF-a) comprising a synthetic amino acid at select locations in pINF-a and a one or two amino acid insertion in the N-terminus after removal of the signal peptide. The pINF-a variants can further be pegylated. Methods of making and administering these compounds to treat virus infections in pigs and formulations comprising the variants are also provided.
