VIVOSCRIPT, INC.; INC.;OREGON HEALTH AND SCIENCE UNIVERSITY;VIVOSCRIPT
发明人:
ZHU, YONG,WU, SHILI,BAO, JUN,CHU, CONG-QIU
申请号：
EP12814129
公开号：
EP2734622A4
申请日:
2012.07.19
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
The present inventions are directed to compositions and methods regarding the reprogramming of other cells (such as embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), MSCs, fibroblasts, hematopoietic stem cells, endothelian stem cells, adipocytes, chondrocytes, osteoblasts, osteoclasts and endothelial cells) into chondrogenic cells without introducing exogenous genes to the samples. In particular, the present inventions are directed to transducible materials that are capable of transducing into the biological samples but are not genes or causing genetic modifications. The present inventions also are directed to methods of reprogramming the path of biological samples or treating diseases using the tranducible compositions thereof.
