The Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada
发明人:
申请号:
EP14804229.4
公开号:
EP3003301A4
申请日:
2014.05.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed are inhibitors of lysine-specific demethylase I (LSD1); synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating cancers characterized by the presence of Sox2 using the compounds and compositions Also disclosed are methods of treating cancers characterized by the presence of Sox2 using inhibitors of LSD1 and/or histone deacetylation I (HDAC1). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.