A vacuum packaging machine (1) is described, with internal and &ldquosous vide&rdquo cooking chamber composed of a supporting and containing structure (3) comprising at least one decompression chamber (7) for vacuum packaging and/or cooking a product (6) inside at least one bag (8) or other suitable container, such chamber (7) being composed of at least one tank (2) adapted to be closed by at least one cover (9), the cover (9) being equipped with a welding system (13) of the initially open edges (10) of the bag (8) composed of at least one welding bar (15) and at least one membrane system (16), and comprising at least one bulkhead (17) adapted to be inserted inside the tank (2) of the chamber (7), such bulkhead (17) being equipped on its top with at least one abutment bar (19) of the welding bar (15).