A child resistant and/or senior friendly dispensing system may include a housing, an insert plate for attaching multiple unitary dose containers and that can slide in and out of the housing and a locking means for locking the insert plate to the housing. The locking means may include a locking clip that can extend or retract to realize locking or releasing of the insert plate. The locking means enables a user to open the insert plate only when squeezing the locking clip inward with sufficient force with one hand and pulling the insert plate with another hand simultaneously. The housing may have one or more locking holes on the side walls and the locking clip may have one or more locking tabs positioned to mate with the locking holes. The system may have a sensor network and a circuitry to monitor the dispensing of unitary dose and output the result.