A system and method for the controlled transport of biological samples are disclosed, wherein the system comprises a container including a main body, a cover, an opening/closure control device, a temperature sensor, an electronic board configured for collecting data acquired by said temperature sensor and for controlling a state and operation of said opening/closure control device, and a biological sample content detector controlled by said electronic board. The system further comprises a server including a database; and the electronic board includes a communication module configured for sending to said server, during transport, a series of data at least about the content of the container and the internal temperature thereof, for the storage of said series of data in the database of the server. The biological sample content detector may be a proximity sensor configured for detecting the presence of the biological samples inside the container.
