O'Shannessy, Daniel J.,Grasso, Luigi,Wan, Shanhong,Chao, Qimin,Somers, Elizabeth Brooke,OShannessy, Daniel J.
申请号:
AU2011323124
公开号:
AU2011323124C1
申请日:
2011.11.04
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
The present invention provides methods and kits for assessing whether a subject is afflicted with an FRα-expressing cancer, methods and kits for predicting the progression of ovarian cancer in a subject afflicted with an FRα-expressing cancer, methods and kits for assessing the level of risk that a subject will develop an FRα- expressing cancer, and methods of stratifying a subject with an FRα-expressing cancer into cancer therapy groups. The methods involve determining the level of folate receptor alpha (FRα) which is not bound to a cell in a sample derived from the subject and comparing this level with the level of FRα in a control sample.