Elizabeth Brooke Somers;Daniel J. O'Shannessy;Shanhong Wan;Luigi Grasso;Qimin Chao;Daniel J. OShannessy
发明人:
Daniel J. O'Shannessy,Luigi Grasso,Shanhong Wan,Qimin Chao,Elizabeth Brooke Somers,Daniel J. OShannessy
申请号：
US13289892
公开号：
US20120207771A1
申请日:
2011.11.04
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides methods and kits for assessing whether a subject is afflicted with an FRα-expressing cancer, methods and kits for predicting the progression of ovarian cancer in a subject afflicted with an FRα-expressing cancer, methods and kits for assessing the level of risk that a subject will develop an FRα-expressing cancer, and methods of stratifying a subject with an FRα-expressing cancer into cancer therapy groups. The methods involve determining the level of folate receptor alpha (FRα) which is not bound to a cell in a sample derived from the subject and comparing this level with the level of FRα in a control sample.
