The present invention provides an 8-oxoadenine compound having immunemodulating activities such as an interferon inducing activity and useful as an antiviral agent and antiallergic agent, which is represented by the following formula (1): [wherein the ring A represents a 6-10 membered aromatic carbocyclic ring and the like, R represents a halogen atom, an alkyl group and the like, n represents an integer of 0-2, Z 1 represents alkylene, X 2 represents oxygen atom, sulfur atom, SO 2 , NR 5 , CO, CONR 5 , NR 5 CO and the like, Y 1 , Y 2 and Y 3 represent independently a single bond or an alkylene group, X 1 represents oxygen atom, sulfur atom, NR 4 (R 4 is hydrogen atom or an alkyl group) or a single bond, R 2 represents a substituted or unsubstituted alkyl group, R 1 represents hydrogen atom, hydroxy group, an alkoxy group, an alkoxycarbonyl group or a haloalkyl group] or its pharmaceutically acceptable salt.本發明提供一種具有免疫調節活性(諸如干擾素誘導活性)且能有效用作抗病毒劑及抗過敏性劑之8-氧基腺嘌呤化合物或其藥理學上可接受之鹽,該化合物由下式(1)代表:[其中環A代表6-10員芳族碳環及其類似物,R代表鹵素原子、烷基及其類似物,n代表0-2之整數,Z1代表伸烷基,X2代表氧原子、硫原子、SO2、NR5、CO、CONR5、NR5CO及其類似物,Y1、Y2及Y3獨立代表單鍵或伸烷基,X1代表氧原子、硫原子、NR4(R4係氫原子或烷基)或單鍵,R2代表經取代或未經取代之烷基,R1代表氫原子、羥基、烷氧基、烷氧基羰基或鹵基烷基]。
