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molecular targets for the prevention and / or treatment of fibrosis, hypertrophic scars and keloids
专利权人:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE);CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.);ECOLE NORMALE SUPERIEURE;UNIVERSITÉ PARIS DIDEROT - PARIS 7;URGO RECHERCHE IN
发明人:
CLAIRE DUGAST-DARZACQ,MAÏTÉ NOIZET,XAVIER DARZACQ
申请号:
BR112016002524
公开号:
BR112016002524A2
申请日:
2014.07.30
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to a therapeutic compound comprising: an agent that inhibits the activity of at least one gene selected from the group consisting of foxs1, creb5, hic1, irf7, pou2f2, stat4, tcf4, and / or an agent increases the activity of at least one gene selected from the group consisting of maf, meox2, six2 for use in the prevention and / or treatment of fibrosis, hypertrophic scarring, and keloid.a presente invenção se refere a um composto terapêutico compreendendo: um agente que inibe a atividade de pelo menos um gene selecionado de entre o grupo que consiste em foxs1, creb5, hic1, irf7, pou2f2, stat4, tcf4, e / ou um agente que aumenta a atividade de pelo menos um gene selecionado de entre o grupo consistindo em maf, meox2, six2 para uso na prevenção e/ou tratamento de fibrose, cicatriz hipertrófica e queloide.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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