Tamper Resistant Co-Extruded Dosage Form Containing an Active Agent and an Adverse Agent and Process of Making Same

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专利权人:

Purdue Pharma L.P.

发明人:

Robert P. Flath,John K. Masselink

申请号：

US14513585

公开号：

US20150140086A1

申请日:

2014.10.14

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to co-extruded pharmaceutical compositions and dosage forms including an active agent, such as an opioid agonist, and an adverse agent, such as an opioid antagonist. Such compositions and dosage forms arc useful for preventing or discouraging tampering, abuse, misuse or diversion of a dosage form containing an active pharmaceutical agent, such as an opioid. The present invention also relates to methods of treating a patient with such a dosage form, as well as kits containing such a dosage form with instructions for using the dosage form to treat a patient.

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