Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof

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专利权人:

Pfizer Inc.

发明人:

Mark Edward Schnute

申请号：

US15581310

公开号：

US09920054B2

申请日:

2017.04.28

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.

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