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Methyl- and Trifluromethyl-Substituted Pyrrolopyridine Modulators of RORC2 and Methods of Use Thereof
专利权人:
Pfizer Inc.
发明人:
Mark Edward Schnute,Andrew Christopher Flick,Peter Jones,Neelu Kaila,Scot Richard Mente,John David Trzupek,Michael L. Vazquez,Goran Mattias Wennerstal,Li Xing,Edouard Zamaratski,Liying Zhang,Rayomand
申请号:
US16563022
公开号:
US20190387710A1
申请日:
2019.09.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides methyl- and trifluoromethyl-substituted pyrrolopyridines, pharmaceutical compositions thereof, methods of modulating RORγ activity and/or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and pharmaceutical compositions thereof.
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