COMPOSITIONS AND METHODS FOR MODULATING METABOLISM
- 专利权人:
- Jorge Plutzky;James Elliott Bradner;Jonathan Brown
- 发明人:
- James Elliott Bradner,Jonathan Brown,Jorge Plutzky
- 申请号：
- US13697963
- 公开号：
- US20130252331A1
- 申请日:
- 2011.05.16
- 申请国别(地区):
- US
- 年份:
- 2013
- 代理人:
- 摘要：
- The invention provides compositions comprising an effective amount of an agent that inhibits a BET protein (e.g., Brd2, Brd3, Brd4), and methods of using such compositions for treating or preventing metabolic syndrome, obesity, type II diabetes, insulin resistance, and related disorders characterized by undesirable alterations in metabolism or fat accumulation.
- 来源网站：
- 中国工程科技知识中心
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相关专利
- COMPOSITIONS ET PROCÉDÉS PERMETTANT DE MODULER UN MÉTABOLISME
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- Manipulation of hairy and enhancer of split 3 (Hes3) and its regulators/mediators in diabetes, obesity, and metabolic syndrome
- Compounds derived from acid indaniloxi - dihydro - benzofuranil acid Protein coupled receptor agonists, G40 (GPR40)； Salt； Pharmaceutical Composition and use for prophylaxis and / or treatment of Metabolic Diseases such as Diabetes and its associated conditions such as resistance to in Sulina and obesity, among others.
- It is a derivative of cindinidinide hydroxyhydrazine taking GPR40； a synthetic drug； a compound used to treat diseases or diseases such as diabetes, insulin resistance, obesity, etc.
