2-[4-(PYRAZOL-4-YLALKYL)PIPÉRAZIN-1-YL]-3-PHÉNYL PYRAZINES ET PYRIDINES ET 3-[4-(PYRAZOL-4-YLALKYL)PIPÉRAZIN-1-YL]-2-PHÉNYL PYRIDINES COMME ANTAGONISTES DE RÉCEPTEUR 5-HT<;SB>;7<;/SB>;
The present invention provides selective 5-HT7 receptor antagonist compounds of Formula I and their use in the treatment of migraine, persistent pain, and anxiety: where A and B are each independently &mdash;C(H)&boxH; or &mdash;N&boxH;, provided that at least one of A and B is &mdash;N&boxH;, n is 1-3, m is 0-3, and R1-4 are as defined herein.