BARRETT RACHEL,BRODEUR SCOTT,CANADA KEITH A,LITZENBURGER TOBIAS,SINGH SANJAYA
申请号：
NZ60202011
公开号：
NZ602020A
申请日:
2011.03.30
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a humanized CD40 binding antibody, wherein said antibody comprises a heavy chain CDR1 sequence of SEQ ID NO: 11, a heavy chain CDR2 sequence of SEQ ID NO:15 and a heavy chain CDR3 sequence of SEQ ID NO:17； and wherein said antibody comprises a light chain CDR1 sequence of SEQ ID NO:21, a light chain CDR2 sequence of SEQ ID NO:23 and a light chain CDR3 sequence of SEQ ID NO:25. Further disclosed are antibodies comprising said CDR regions and uses thereof ffor treating CD40 mediated immune response diseases or disorders. SEQ ID NO: 11 GFTFSDYGMH SEQ ID NO: 15 YISSGNRIIYYADTVKG SEQ ID NO: 17 QDGYRYAMDY SEQ ID NO: 21 KSSQSLLNSGNQKNYLT SEQ ID NO: 23 WTSTRES SEQ ID NO: 25 QNDYTYPLT
