Oligosaccharides comportant un groupe amino-oxy et conjugués associés

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专利权人:

Genzyme Corporation

发明人:

申请号：

EP11188506.7

公开号：

EP2457920B1

申请日:

2008.01.18

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.

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