Zhu, Yunxiang,Cheng, Seng H.,Jiang, Canwen,Avila, Luis Z.
申请号:
DK11188506
公开号:
DK2457920T3
申请日:
2008.01.18
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
The invention provides methods for the synthesis of oligosaccharides comprising an aminooxy group. The invention further provides oligosaccharides comprising an aminooxy group, methods for coupling oligosaccharides comprising an aminooxy group to glycoproteins, and oligosaccharide-protein conjugates. Also provided are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-protein conjugate.