A method of manufacturing a shoe insole includes an upper cover layer and a lower cover layer conforming in shape to the inner bottom of the shoe, and an insole body retained between the upper cover layer and the lower cover layer, taking a foot sole form to which pads are applied to selected regions of a sole taking a foot sole form; manufacturing an insole frame having a shape conforming to a three-dimensional shape of the foot sole form and applying insole pads to an upper surface of the insole frame, based on positions of marks of the test pads of the foot sole form to which the pads are applied, wherein the insole body includes the insole frame to which the insole pads are applied.