The present disclosure relates to a method of preventing and/or treating pulmonary vascular disease and/or right ventricular dysfunction, including but not limited to pulmonary hypertension or pulmonary arterial hypertension, comprising administering a therapeutically effective amount of an ASK1 inhibitor.本發明揭示係關於一種防止及/或治療肺血管疾病及/或右心室功能異常之方法,肺血管疾病及/或右心室功能異常包含,但不局限於肺高血壓或肺動脈高血壓,該方法包含給予治療有效量的ASK1抑制劑。