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Isolation of pulmonary arterial endothelial cells from patients with pulmonary vascular disease and uses thereof
专利权人:
Allegheny-Singer Research Institute
发明人:
Michael J. Passineau,Srinivas Murali,Raymond L. Benza,Jonathan B. Pollett
申请号:
US14426488
公开号:
US09835617B2
申请日:
2013.09.10
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present disclosure provides methods of obtaining, recovering and culturing pulmonary arterial endothelial cells from an individual patient, subjected to a right heart catheterization in regard to diagnosis of pulmonary hypertension. These isolated pulmonary arterial endothelial cells from an individual patient may be utilized to generate cellular phenotyping profile for the cell population, allowing generation of a personalized pharmacotherapy regime to assist the clinician in treatment and prognosis of the disorder for an individual patient.
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