TRICYCLIC PYRIMIDINE DERIVATIVES AS WNT ANTAGONISTS

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专利权人:

Michael Boutros;Florian Fuchs;Sandra Steinbrink;Rajendra-Prasad Maskey;Corinna Koch;Daniel Gilbert

发明人:

Florian Fuchs,Daniel Gilbert,Corinna Koch,Rajendra-Prasad Maskey,Sandra Steinbrink,Michael Boutros

申请号：

US13380459

公开号：

US20120157481A1

申请日:

2010.06.25

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to compounds having the general formula (I) with the definitions of X1-X3, Y1, Y2, L1, R1 and R2 given below and/or solvates, hydrates, esters and pharmaceutically acceptable salts thereof. Furthermore, the invention relates to the use of said compounds for modulating of the Wnt signalling pathway activity and their use as a medicament, preferably for the treatment of cancer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/