Compounds derived from pirido [4,3-d] pyrimidine, as inhibitors of MEK; Pharmaceutical composition that comprises; and its use for the treatment of inflammatory diseases, Infections, autoimmune disorders, Metabolic Diseases and malignant diseases, among others.
The present disclosure is related to heteroaryl compounds as MEK inhibitors. These compounds include heteroaryl compounds of formula I, their pharmaceutically acceptable salts, combinations with suitable medicament and pharmaceutical compositions thereof. The present disclosure also includes processes of preparation of the compounds and their use in methods of treatment. The compounds as disclosed herein are of Formula (I) below:<;p>;LA SOLICITUD SE REFIERE A COMPUESTOS DERIVADOS DE PIRIDO[4,3-D]PIRIMIDINA, INHIBIDORES MEK; COMPOSICIÓ;N QUE LOS COMPRENDE; Y SU USO EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS, AUTOINMUNE, NEUROLÓ;GICAS, METABÓ;LICAS, PROLIFERATIVAS, ENTRE OTRAS<;/p>;